5 EASY FACTS ABOUT PKRRATING DESCRIBED

3B). R526 through the loop among αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the main chain carbonyl of R413. The tip with the activation segment is stabilized by a hydrogen bond involving Y454 and E480 from αfile.